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Michelson Diagnostics (MDL) the leading provider of clinical OCT imaging systems announces that it has now developed a probe suitable for imaging soft tissue for use with its VivoSight Multi-Beam optical coherence tomography (OCT) imaging system.  The probe will allow in vivo imaging of oral and gynaecological tissue.

The VivoSight Multi-Beam OCT system provides sub-surface cross-sectional images at far higher resolution than is possible with ultrasound, CT or MRI, and much deeper and wider than is possible with confocal microscopy. The new Soft Tissue Probe provides the same unprecedented imaging quality as the Topical Probe, with real time, in vivo images at better than 7.5 µm lateral resolution.  The probe is 9 cm long and provides both 2D and 3D images over a 5 mm x 5 mm area.  For sterile applications, the probe is used with a disposable transparent sheath which covers the probe, handle and upper connecting cable.

The structures of the epithelial layers are exquisitely revealed in amazing detail, says Jon Holmes, CEO of Michelson Diagnostics.   The new probe promises to be a tremendous aid to clinicians for the diagnosis and treatment of oral and cervical cancers.

Ex vivo trials on excised oral tissue have shown that Multi-Beam OCT can visualize structures such as the epidermal / dermal junction and areas of cellular crowding characteristic of early stage tumours.  Michelson's clinical partners have reported achieving sensitivity of 80 per cent and specificity of 81 per cent for diagnosis of oral cancer, from a blinded assessment of OCT images of 125 excised oral lesions1. It is expected that in vivo imaging will give even better results and could eliminate the need for a biopsy.  The probe will also be suitable for imaging tumour margins prior to surgery.

Download a datasheet on the Soft Tissue Probe by clicking here

VivoSight image of cheek mucosa.

Note clear epithelium boundary.

Soft Tissue Probe